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Atopic Dermatitis

Atopic Dermatitis: Welcome

Eczema is only a descriptive term to describe the appearance of a rash. It is not a diagnosis per se. The following information is designed to help clarify if the “eczema” you are experiencing is atopic dermatitis. Doctors use very specific criteria to confirm that your eczema is not due to other causes like a fungal infection, irritation due to a chemical, etc.

Diagnostic criteria for atopic dermatitis (proposed by Hanafin and Lobitz) include itching, eczema appearance and long lasting. It must also have past or family history of atopy, skin test reactivity, white dermatographism and/or delayed blanch to cholinergic agents, a particular type of cataracts (anterior subcapsular). Confirming features include xerosis/hyperlinear palms, white patches on cheeks (pityriasis alba), rough bumpy skin on back of arms (keratosispilaris), dark circles under the eyes (infraorbital congestion)darkening an extra crease under the eye called a Dennie-Morgan fold, elevated total blood IgE level, a deformity of the cornea called keratoconus, a tendency toward nonspecific hand dermatitis , and a tendency toward repeated cutaneous infections.

Some other causes of eczema include:

  • Seborrheic dermatitis

  • Contact dermatitis

  • Nummular dermatitis

  • Scabies

  • Psoriasis (guttate form in children often associated with acute streptococcal infection

  • Immunodeficiency states

  • Histiocytosis X (infantile form is called Letterer-Siwe disease and is characterized by scaly waxy eruption of the scalp, nape, underarms (axilla), and groin. Resembles seborrheic dermatitis but usually displays purpura and may have signs of hepatosplenomegaly, lymphadenopathy, and weight loss. Skin biopsy shows atypical histiocytes.)

  • Acrodermatitis enteropathica (erosive weeping patches about the mouth, perineum, and acral areas. Always with diarrhea and failure to thrive. Low serum zinc confirms.)

Complications of Atopic Dermatitis include secondary infections with Streptococci, Staphylococci, dermatophytes, and viruses. Impaired delayed hypersensitivity may be the cause of increased incidence of warts and molluscum. Life threatening HSV (eczema herpeticum) or vaccinia (eczema vaccinatum) may occur. Contact dermatitis occurs more commonly. The need and complications associated with corticosteroids.

Home management of acute flares: wet, cool dressings soaked with aluminum acetate (Burrow’s solution, Domeboro’s ) and normal saline or tap water for oozing, crusted, and exudative lesions. Apply 20- 30″ every 4-6 hours. Evaporative action causes vasoconstriction, reduces itching and inflammation. Tepid water baths with oatmeal (plain or oilated Aveeno), starch, tar (LCD, Zetar, Balnetar), or bath oil (added after patient immersed for 10-20″ to allow hydration of keratin layers) also reduces itching and inflammation. These can be used in addition to wet dressings or as a substitute. Between dressings and/or baths, small amounts of topical corticosteroids should be applied to affected areas. Fluorinated steroids should not be used in the face or groin due to their potential for atrophy and visible spider-like veins (telangiectasias). Use antihistamines to allow you to relax and to reduce itching.


BATHING INSTRUCTIONS: Bathing is better than showering, and bathing at is best. Soap should not be used in the tub; wash armpits and groin with mild cleansers (Dove, Aquanil, Aveeno, etc.) with a moist white cotton diaper at the sink. Avoid areas that are active. Remove all cleanser with a separate moist diaper before entering the bathtub.

Bathe in lukewarm (tepid) water for 10-15 minutes every other day. Try to remain immersed under water as much as possible. Do not use any additives in the water.

Immediately upon getting out of the tub, apply moisturizing lotions while your skin is still damp. Pat dry the excess water; rubbing will not only remove the moisturizing cream but may irritate your skin. Use an all cotton Turkish towel that has been washed in mild soap (see below).

SCALP CARE: If the scalp is involved, Sebulex, Ionil, Fostex, or Zincon shampoo should be used for 5 – 10 minutes before rinsing thoroughly. If possible, shampooing should be performed over the sink rather than in the shower.

GENERAL MEASURES: Reducing irritation, sweating, sweat gland blockage, and itching are important. Loose fitting 100% cotton is best. Avoid all wool, mohair, and silk. Wash all of your clothes, sheets, blankets, towels, etc. with a mild soap (We used to recommend Dreft and Ivory Flakes but Ivory Snow ceased to be a soap flake product ~10 years ago and is a detergent just like all the others.  Many of the medical professionals making recommendations do not know this. Dreft is also not a soap flake, it is a detergent (in fact, I think the first one invented).  It is not a very powerful
detergent, which is why it is less irritating than many on the market
today, but it is more problematic than true soap flakes for infants
with eczema or the potential for eczema. There are companies that
still make old-fashioned soap flakes. Thanks to A.J. Lumsdaine for this information) and be sure to rinse thoroughly. Fabric softeners, bleach, starch, and strong detergents should be avoided. Wash all new clothes before wearing for the first time.

Try to keep the temperature of the home and work steady, especially in the bedroom. Temperature changes and overheating may aggravate your eczema by increasing sweating, dryness, and itching. Increasing the humidity by adding a humidification unit to your central heating system or using a portable humidifier during dry periods (such as the winter when the heating system dries the air in your home) may be beneficial for you. It is very important, however, to keep your humidifier clean and free of mold.

Emotional stress and fatigue often seem to flare eczema. Stability and harmony at home, work, or school can help tremendously.

Because patients with eczema are susceptible to a particular type of skin bacteria (Staph. aureus), keeping fingernails trimmed and clean reduces the chance of infecting your eczema.

FOODS and DIET: While the role of food allergy in eczema remains controversial, there is increasing evidence that avoiding certain foods during early infancy may reduce the risk of developing allergies, eczema, and allergic asthma. Since breast milk passes many of the protein allergens eaten by the mother, dietary restriction during lactation may be worth considering. The foods most commonly implicated include eggs, cow’s milk, wheat, chocolate, corn, nuts, fish, and citrus fruits. Deciding which foods to avoid requires trial and observation.

Once eczema has developed, the relationship of food to causing or exacerbating eczema is less clear. Egg whites are often implicated as an important factor in eczema, even if the skin test did not show a true “allergy.” Strawberries, foods with a high nitrate content such as potato chips and other highly seasoned foods, crawfish, lobster, alcoholic beverages, certain medications (codeine, Demerol, hydrocodone, barbiturates, etc.) release factors (histamine) which may aggravate eczema. Other foods contain factors (histamine, tyramine) which may aggravate itching and eczema. These include tomatoes, citrus fruits, spinach, soybean proteins, chocolate.

Complete avoidance of all these foods for two to four weeks should be considered. Keep a diary to determine what changes have occurred, if any. If any change is noted, then one particular food can be added back into the diet every two weeks. Continue your diary. If the eczema gets worse (itching, redness, or size of eczema), stop that particular food and wait an additional week or two before trying a different food.

SPECIFIC MEDICATIONS: Eczema is often called the itch that rashes. Thus, one of our goals is to reduce itching with an antihistamine. Since most people itch especially at night and many antihistamines cause drowsiness, we recommended an increased dose at night.

As mentioned above, patients with eczema are especially susceptible to skin infection with bacteria (Staph. aureus) and certain viruses (Herpes, molluscum, etc.) and fungi. During a flare of eczema, an antibiotic ointment or pill may be recommended. If you have a flare and a fever, call the doctor for further instructions.

The inflammation seen in eczema may require a topical steroid cream or ointment. These medications should be used sparingly but frequently. Caking the medication on the affected area is less effective than gently rubbing it into the eczema. When an ointment is prescribed, it is usually for especially difficult, dry, or scaly areas. Ointments should not be used on the face or groin, or areas that appear moist or weepy.

Occasionally a short course of systemic steroids (prednisone, etc.) are required to control a severe exacerbation. While the effects are usually dramatic, long term use of systemic steroids is to be avoided because of serious and often irreversible side effects.

THE NATURAL COURSE OF ECZEMA: When eczema appears within the first year of life (the infantile form), about 2/3 clear spontaneously by 3 – 5 years of age. If the eczema appears in an older child, many still recover completely by the age of 10. Unfortunately 1 in 2 develops hay fever (allergic rhinitis) and up to 1 in 3 develops bronchial asthma.

COMPLICATIONS: Infections of the skin are a frequent complication and must be treated with either a prescription antibiotic or an effective anti-microbial. Because of an increased susceptibility to Herpes, you should stay clear of people with active Herpes, cold sores, etc. or consider using nutritional support that reduces Herpes replication.

NON-DRUG MANAGEMENT OF ECZEMA is a slow process that requires an individualized and comprehensive approach. The use of specific essential fatty acids, bowel flora optimization, dietary restrictions, nutritional support, Traditional Chinese medicine and homeopathic remedies are often recommended.

Atopic Dermatitis: Welcome
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